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KMID : 0359920070260040465
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Korean Journal of Nephrology
2007 Volume.26 No. 4 p.465 ~ p.468
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A Case of Cystadenocarcinoma of the Pancreas in a Patient with Autosomal Dominant Polycystic Kidney Disease
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Yang Young-Joon
Jang Dong-Seok
Lee Young-Mo
Na Ki-Ryang
Lee Byung-Seok
Lee Kang-Wook
Shin Young-Tai
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Abstract
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Polycystic kidney disease is an autosomal dominant disease that may be associated with liver and pancretic cysts. Mitral valve prolapse and intracranial berry aneurysms are also well-known manifestations of autosomal dominant polycystic kidney disease (ADPKD). Cystadenocarcinoma of the pancreas is uncommon and accounts for only 1% of primary pancreatic malignancies. Few cases were reported to have an association of ADPKD and pancreatic malignancies. We report a 63-year-old man with ADPKD who was admitted to our hospital with anorexia and severe weight loss. After abdominal CT and histologic examination, he was diagnosed as pancreatic cystadenocarcinoma with lung, spleen, and liver metastasis. To prolong the life of the patient, we tried gemcitabine and cisplatin combination chemotherapy. But the patient died 2 months after diagnosis due to the disease progression.
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KEYWORD
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Polycystic kidney diseases, Pancreatic neoplasms, Cystadenocarcinoma
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